Nipah virus confirmed in Kerala fever outbreak as toll rises to 10, 20 others under observation Monday May 21,2018

With the death of two more persons early Monday May 21,2018, the toll in a Nipah virus-induced fever in North Kerala rose to 12

Two of the deaths took place in the Kozhikode Medical College and two others died at the taluk hospital

The Union Health Ministry has rushed a team of experts to assist the state which is struggling to cope with the outbreak

“A team from the Indian Council of Medical Research is arriving in Kozhikode on Monday. We are trying our best to contain the spread of virus and we sought help from all,” said State Health Secretary Rajeeve Sadanandan

“The National Virology Institute in Pune has confirmed that the dead were infected with Nipah virus,” R L Saritha, state health director said Sunday night May 20,2018

This is the first time the virus which has high fatality rate and spreads mainly through bats, pigs and other animals has been detected in Kerala. There is no vaccine or medicine for the disease and only form of treatment is supportive medicines and palliative care.

At least 12 people are admitted in various hospitals and 20 others are under observation. Many families who were staying closer to the affected dwellings have been evacuated to safer places and domestic animals are also under observation

THE VIRUS
Nipah virus (NiV) infection is a newly-emerging zoonosis (a disease which can be transmitted to humans from animals) that causes severe disease in both animals and humans. The natural host of the virus are fruit bats of the Pteropodidae Family, Pteropus genus.
FIRST OUTBREAK
NiV was first identified during an outbreak of disease that took place in Kampung Sungai Nipah, Malaysia in 1998. On this occasion, pigs were the intermediate hosts. However, in subsequent NiV outbreaks, there were no intermediate hosts. In Bangladesh in 2004, humans became infected with NiV as a result of consuming date palm sap that had been contaminated by infected fruit bats. Human-to-human transmission has also been documented, including in a hospital setting in India.
TRANSMISSION
The viruses jump the species barrier and infect a secondary animal host, transmission takes place through direct contact with infected bats, pigs, or from other NiV-infected people and people have been also cautioned that they should not consume fruits that have fallen on to the ground.
SYMPTOMS
NiV infection in humans has a range of clinical presentations, from asymptomatic infection to acute respiratory syndrome and fatal encephalitis. NiV is also capable of causing disease in pigs and other domestic animals. Nipah virus primarily causes an encephalitic syndrome with a high mortality rate. The characteristic MRI abnormalities are multiple, small (less than 5 mm), asymmetric focal lesions in the subcortical and deep white matter without surrounding edema.
TREATMENT
There is no vaccine for either humans or animals. The primary treatment for human cases is intensive supportive care
PRECAUTIONS
Nipah virus infection can be prevented by avoiding exposure to sick pigs and bats in endemic areas and not drinking raw date palm sap and not consuming fruits that have fallen from trees